Title page for etd-0812116-103838


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URN etd-0812116-103838
Author Yu-Chen Hsu
Author's Email Address hs19921005@gmail.com
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Department Mechanical and Electro-Mechanical Engineering
Year 2016
Semester 2
Degree Master
Type of Document
Language English
Title Oxygen Transport in Blood Flows in a Mini-Oxygenator:
a Computational Fluid Dynamics Study on Artificial Lung
Date of Defense 2016-07-26
Page Count 60
Keyword
  • fiber
  • artificial lung
  • non-Newtonian flow
  • oxygen transport
  • pulsating flow
  • Abstract The target of this research is to computationally analyze deoxygenated blood flows passing through a multi-fiber bundle that releases oxygen to blood. The effect of pulsatile flow on the oxygen transport in blood is investigated. Dimensionless parameters for the physical model include Reynolds numbers (Re), Womersley parameters (α), pulsation amplitudes (A). The power law model is used to describe the non-Newtonian flow and the Hill equation is employed to simulate the oxygen saturation of hemoglobin. It is observed that flow pulsation significantly influences the velocity profile, partial pressure of oxygen (PO2), saturation of oxygen (SO2) and Sherwood numbers, in blood flows along a fiber bundle region. As blood flows into fiber bundle region, the downstream sinusoidal profiles of O2 partial show the phase lag with respect to that at the entrance. The variations of SO2 and PO2 boundary layers are documented. Finally, the mixing length where PO2 achieves 100 mmHg is determined against different Reynolds numbers.
    Advisory Committee
  • Hsu, Shen-Yen - chair
  • Chien-Chou Tseng - co-chair
  • Shin-Pon Ju - co-chair
  • Sodio C. N. Hsu - co-chair
  • Kuang C. Lin - advisor
  • Files
  • etd-0812116-103838.pdf
  • Indicate in-campus at 5 year and off-campus access at 5 year.
    Date of Submission 2016-09-12

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