Title page for etd-0711106-165522


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URN etd-0711106-165522
Author Deng-hao Liang
Author's Email Address m933040041@student.nsysu.edu.tw
Statistics This thesis had been viewed 5564 times. Download 2918 times.
Department Computer Science and Engineering
Year 2005
Semester 2
Degree Master
Type of Document
Language zh-TW.Big5 Chinese
Title Investigation of quantitative absolute concentrations of in vivo proton magnetic resonance spectroscopy
Date of Defense 2006-06-16
Page Count 55
Keyword
  • Partial volume effect
  • Proton magnetic resonance spectroscopy
  • Absolute quantification
  • Abstract Magnetic resonance spectroscopy has been widely used in medical applications, rendering precise evaluation and diagnosis in clinics. As the development of various tools for automatic spectra analysis, providing objective quantification of metabolites, absolute concentrations has been playing an important role in clinical studies and applications as well. 
     In this study, we investigate the reliability and accuracy of absolute concentration quantified by LCModel. Ten healthy subjects were included. We compared the resultant concentrations calculated by internal water scaling and phantom calibration, both of which are provided by LCModel. Partial volume effect was also taken into account to improve the accuracy of absolute concentrations. Automatic segmentation was applied to volume of interest in order to separate gray matter and white matter, which will facilitate the further partial volume correction and thus better accuracy of absolute quantification.
    Advisory Committee
  • Chung-nan Lee - chair
  • Yi-Ruei Liu - co-chair
  • Yi-Ru Lin - co-chair
  • Cheng-Wen Ko - advisor
  • Files
  • etd-0711106-165522.pdf
  • indicate accessible in a year
    Date of Submission 2006-07-11

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