Title page for etd-0702116-161607


[Back to Results | New Search]

URN etd-0702116-161607
Author Jheng-jhong Lai
Author's Email Address No Public.
Statistics This thesis had been viewed 5335 times. Download 17 times.
Department Materials and Optoelectronic Science
Year 2015
Semester 2
Degree Master
Type of Document
Language English
Title Evaluation of tantalum-based metallic glass potentials for bio-implant applications and their special cell attachment mechanism
Date of Defense 2016-07-14
Page Count 119
Keyword
  • simulated body fluid
  • corrosion resistance
  • metallic glasses
  • thin film
  • biocompatibility
  • Abstract Because of the excellent mechanical properties and outstanding corrosion resistance, metallic glasses have been rapidly developed and wide studied. Additionally, according to previous studies, tantalum owns good biocompatibility: the number of cell adhesion is more than pure titanium and has no obvious cytotoxicity. Nonetheless, few Ta-based metallic glasses were designed for biomedical application. This study is devoted to evaluating the potential of Ta-based metallic glasses utilized in bio-implant application by following methods. First, the corrosion properties of Ta-based metallic glasses are estimated by electrochemical analyses. Materials with high corrosion resistance indicate that the little possibility of failure generates after long-term use. Second, the mechanical properties, such as Young’s modulus and hardness, are measured with a view to discussing the influence of shielding effect and wear resistance. Optimize Young’s modulus restrain stress from transferring to implanted materials and the bone mineral density will decrease without stress stimulating. High wear resistance can decrease the debris releasing after long-term use, which brings about stimulating the immune system and inflammatory responses. Last not the least, by cell viability and cell adhesion, the biocompatibility of Ta-based metallic glasses are evaluated. Furthermore, the factors that influence cell adhesion will be discussed.
    Advisory Committee
  • Che-Hsin Lin - chair
  • J. S. C. Jang - co-chair
  • J. C. Huang - advisor
  • Files
  • etd-0702116-161607.pdf
  • Indicate in-campus at 2 year and off-campus access at 2 year.
    Date of Submission 2016-08-02

    [Back to Results | New Search]


    Browse | Search All Available ETDs

    If you have more questions or technical problems, please contact eThesys