||Carbon dots is a very novel nanomaterial with fluorescence property. It has multiple characteristic, such as : easily and facile synthesis, good water solubility, chemistry inert, lower toxic, surface functionalize and resisting photobleaching. Therefore, with all the superioritys, carbon dots can apply in many research regions, like : photocatalysis, photoluminescence, chemosensors, metal ions probes, biosensors, bioimaging even in the drug delivery system.|
This thesis is about using polypyrrole functionalize carbon dots(PPy-Cdots) to detect melatonin. Polypyrrole is a conducting polymer, it has three main properties to functionalize it to our synthesis carbon dots. The first one is good biocompatible property that reducing the error from the environment. The second is well signal transferring. No matter what importing or exporting signals, it will not easily influence by functionalize agent itself. The third it can protect carbon dots from polluting and let the analysis result inaccurate. Melatonin is a hormone that is general presence in organisms. It can affect our biological rhyme, natural rest. It also has functions of anticancer and increased immunity. Recently, melatonin is already applied in curing many kinds of diseases, for instance: insomnia and depression. As a result, detecting the quantity of melatonin in human body is an important subject.
As a consequence, we synthesis a polypyrrole functionalize catbon dots, not only make the luminescence increased but also preventing interference from possible resources. Melatonin has similar absorbance region with our sample, so partial energy will absorb by analytes when sample excited by laser cause quenching effect happened. Later, we use this phenomenon to quantify the amount.