|Author's Email Address
||This thesis had been viewed 5561 times. Download 0 times.|
||Computer Science and Engineering|
|Type of Document
||Simultaneously Optimized Control Pins Placement and Channels Routing of Control-Layer in Flow-Based Microfluidic Biochips|
|Date of Defense
||Due to the advances in micro-electromechanical systems (MEMS), the lab-on-a-chip (LOC) has been developed. There are many applications of lab-on-a-chip devices, including point-of-care disease diagnostics, medicine analysis and drugs discovery. |
The flow-based microfluidic biochip is one kind of lab-on-a-chips. On microfluidic biochip platform, digital microfluidic biochip and flow-based microfluidic biochip are the two major categories of implementation. On digital microfluidic biochip platform, the droplets are manipulated on an array of electrodes. However, there are many microchannels on flow-based microfluidic biochip and the reactants are manipulated in these closed microchannels. Our proposed microfluidic chip design flow is on the flow-based microfluidic biochip platform.
The design procedures of lab-on-a-chip today are by manual owing to lack of computer-aided design tools. Manual design procedures are time consuming and make the developments less efficient. There may be human errors as the designs become complex.
This research proposes a systematic design procedure for the control layer of flow-based microfluidic biochip. The designers would find the solutions more efficient and prevent human errors through the proposed design procedure. This research mainly considers the skew, matching rate and control pin numbers during the design process. Compared to previous works, our proposed method gets 18.5X improvement in skew, 41% improvement in latency and 49% improvement in matching rate.
||Tsung-Yi Ho - chair|
Chung-Nan Lee - co-chair
Wei-Kuang Lai - co-chair
Shu-Min Li - advisor
Indicate in-campus at 99 year and off-campus access at 99 year.|
|Date of Submission