本研究運用Hypercube創新模式，分析從遠距健康照護（Tele-health care）、電子健康照護（E-health care）到行動健康照護（M-health care）的創新演變過程中，對健康照護的二個核心構面：健康照護資訊學（healthcare informatics）與醫療遞送模式（medical related delivery model）所產生的變革與影響。藉由比較與分析各項構面的差異性與創新程度，進而探討該變革對健康照護體系中重要的參與者：顧客、醫院、互補性供應商（complementary providers）及監督管理機構（regulators）可能產生的衝擊。
研究結果顯示，從遠距健康照護到電子健康照護的變革，對病患等健康照護顧客與政府等監督管理機構而言，是一種結構式（architectural）的創新；而對醫院及提供醫療資材與相關支援性服務的互補性供應商則屬於突破式（radical）的創新。等監督管理機構則屬於結構式的創新。此外，從電子健康照護到行動電子健康照護的創新，對顧客及醫院而言，是屬於結構式的創新；對互補性供應商屬於突破式，對監督管理機構則屬於衝擊較小的模組式（modular）創新。
基於上述的分析基礎，本研究最後歸納出成功採用各項健康照護創新的關鍵性能力，並對每一個參與者提出了因應變革的策略性建議，以協助其有效管理新一波的變革衝擊。

This study utilizes a hypercube innovation model to analyze the changes in both healthcare informatics and medical related delivery processes based on the innovations from Tele-health care, E-health care, to M-health care. Further, the critical impacts of the E-health innovations on the stakeholders: healthcare customers, hospitals, healthcare complementary providers, and healthcare regulators are identified.
These results indicate that the innovation from Tele-health care to E-health care is architectural for healthcare customers, radical for both hospitals and healthcare complementary providers, and architectural for healthcare regulators. From E-health care to M-health care, innovation is architectural for both healthcare customers and hospitals, racial for healthcare complementary providers, and modular for healthcare regulators.
Thereafter, the critical capabilities and suggestions for adopting each innovation are discussed

Abstract Ⅱ
Chinese Abstract Ⅲ
Table of Contents Ⅳ
List of Figures Ⅴ
List of Tables Ⅵ
Chapter 1. Introduction 1
1.1 Background and Motivation 1
1.2 Objective 2
1.3Procedures 3
1.4Structure of This Thesis 5
Chapter 2. Literature Review 7
2.1 Tele-healthcare 8
2.2 E-healthcare 8
2.3 M-healthcare 9
2.4 Innovation Model 10
2.4.1 Static Innovation Model 10
2.5 Hypercube Innovation Model 12
Chapter 3. The E-health Hypercube Innovation Model 15
3.1 Comparison of Tele-, E-, and M-healthcare 18
3.1.1 Analysis by Healthcare Informatics 18
3.1.2 Analysis by Medical Related Delivery Model 24
3.2 The E-health Innovation Hypercube 30
3.2.1 Innovation from Tele-healthcare to E-healthcare 30
3.2.2 Innovation from E-healthcare to M-healthcare 32
Chapter 4. The Impact of the E-health Innovations on Stakeholders 34
4.1 Impact of The E-Health Innovations on Collaborative Partners 34
4.1.1 Healthcare Customers 34
4.1.2 Healthcare Complementary Providers 35
4.1.3 Healthcare Regulators 36
4.1.4 Impact of The E-Health Innovations on Hospitals 37
Chapter 5. Conclusion 40
References: 42

Aarts, J. and Peel, V. “Using a descriptive model of change when implementing large scale clinical information systems to identify priorities for future research”, International Journal of Medical Informatics, Vol. 56, 1999, pp. 43-50.
Abernathy, W.J. and Clark, K. 1985. “Innovation: mapping the winds of creative destruction”, Research Policy (14), 1985, pp.3-22
Afuah, A. “Innovation Management: Strategies, Implementation, and Profits”. New York: Oxford University Press, Inc. 1998
Afuah, A. and Bahram, N. 1995. “The hypercube of innovation”, Research Policy (24), 1995, pp.51-76.
Afuah, A. and Tucci, C. L. 2003. “Internet Business Models and Strategies: Text and Cases 2/e”. New York: McGraw-Hill, 2003
Anckar, B. and D’Incau, D. “Value-added services in mobile commerce: an analytical framework and empirical findings from a national consumer survey”, Proceedings of the 35th Hawaii International Conference on System Sciences, Hawaii, USA, 7-10 January. 2002.
Ammenwerth, E., Buchauer, A., Bludau, B., and Haux, R. “Mobile information and communication tools in the hospital”, International Journal of Medical Informatics (57), 2000, pp.21-40
Anderson, J.G., Rainey, M.R., and Eysenbach, G. “The Impact of cyber healthcare on the physician/patient relationship”, Journal of Medical Systems (27:1), 2003, pp.67-84.
Andrade, R., Wangenheim, A.V., and Bortoluzzi, M.K. "Wireless and PDA: a novel strategy to access DICOM-compliant medical data on mobile device”, International Journal of Medical Informatics (71), 2003, pp.157-163.
Ball, M.J. and Lillis, J. “E-health: transforming the physician/patient relationship”, International Journal of Medical Informatics (61), 2001, pp.1-10.
Barnes, S. J. “The mobile commerce value chain: analysis and future developments”, International Journal of Information Management (22), 2002, pp.91-108.
Bonder, S. and Zajtchuk, R. “Changing the paradigm for telemedicine development and evaluation: a prospective model-based approach”, Socio-Economic planning Sciences (31:4), 1997, pp.257-280
Chronaki, C.E., Lelis, P., Chiarugi, F., Tripakis D., Moumouris, K, Stavrakis, H., Kavlentakis, G., Stathiakis, N., Tsiknakis, M., and Orphanoudakis, S.C. “An open eHealth platform for health management using adaptable service profiles”, International Congress Series (1268), 2004, pp.295-300.
Demiris, G. “Electronic home healthcare: concepts and challenges”, International Journal of Electronic Healthcare (1:1), 2004, pp.4-16.
Dyer, K.A. “Ethical challenges of medicine and health on the Internet: a review”, Journal of Medical Internet Research (3:2), 2001, pp.e23 <URL: http://www.jmir.org/2001/2/e23/>
Englebardt, S.P. and Nelson, R. “Health Care Informatics: An interdisciplinary approach”, Missouri: Mosby. 2002.
Eysenbach, G. “What is e-health?”, Journal of Medical Internet Research (3:2), 2001, pp.e20 <URL: http://www.jmir.org/2001/2/e20/>.
Hameed, K. “The application of mobile computing and technology to health care services”, Telematics and Informatics (20), 2003, pp.99-106.
Healthcare Information and Management Systems Society: HIMSS Patient Safety Survey, 2003. Available online: http://www.himss.org/content/files/PatientSafetyFinalReport8252003.pdf.
Healthcare Information and Management Systems Society: HIMSS Networking Technology Survey, 2004. Available online: http://www.himss.org/content/files/2004NetworkingTechnologySurvey.pdf.
Henderson, A. and Clark, K. “Architectural innovation: the reconfiguration of existing product technologies and the failure of established firms”, Administrative Science Quarterly (35), 1990, pp:9-30
Henk, J.D. and Chris V.W. “Trauma care system in The Netherlands”, Injury. International Journal of the Care of the Injured (34), 2003, pp.722-727.
Henderson, R.M. and Clark, K.B. “Architectural innovation: the reconfiguration of existing product technologies and the failure of established firms”, Administrative Science Quarterly (35), 1990, pp.9-30
Kannan, P.K., Chang, A.M., and Whinston, A.B. “Wireless commerce: Marketing issue and possibilities”, Proceedings of the 34th Hawaii International Conference on System Sciences, Hawaii, USA, January 3-6, 2001.
LeRouge, C. & Hevner, A. & Collins R. “Telemedicine encounter quality: comparing patient and provider perspectives of a socio-technical system”, Proceedings of the 37th Hawaii International Conference on System Sciences, Hawaii, USA, January 5-8, 2004.
Mieczkowaska, S., Hinton, M., and Barnes, D. “Barries to e-health business processes”, International Journal of Electronic Healthcare (1:1), 2004, pp.47-59.
Moore, M. “The evolution of telemedicine”, Future Generation Computer systems (15), 1999, pp.245-254.
Parente, S.T. “Beyond the hype: A taxonomy of e-health business models”, Health Affair (19:6), 2000, pp.89-102.
Pierre, S. “Mobile computing and ubiquitous networking: concepts, technologies, and challenges”, Telematics and Informatics (18), 2001, pp.109-131.
Rajeswari M. and Dharma P. Agrawal “Current and future applications of mobile and wireless network”. Association for Computing Machinery. Communications of the ACM (45:10), 2002, pp.144.
Rigby, M.J. and Robins, S.C. “Building healthcare delivery and management systems centered on information about the human aspects”, Computer Methods and Programs in Biomedicine (54), 1997, pp.93-99.
Shactman, N. “Why doctors hate the internet”, 2000, Wired News [online] 2000 Apr 10. URL: http://www.wired.com/news/culture/0,1284,35516,00.html [Accessed 2004 May 29].
Smaling, J. “The strategic view of wireless infrastructure”, Health Management Technology (24:11), 2003, pp.32.
Srauss, A. and Corbin, J. “Basis of qualitative research: techniques and procedures for developing Grounded Theory <second edition>”, Sage Publications, Inc. 1998
Terry, N.P. “Improving the legal and regulatory climate for telemedicine and e-health”, International Congress Series (1256), 2003, pp.279-284.
Tessier, C. “Introduction to MoHCA and Mobile Health”, Mobile Healthcare Alliance , Jan, 2003, URL: http://www.mohca.org/presentations/MoHCAintro0103.pdf.
Tessier, C. “An introduction to mobile health care”, Proceedings of the 19th Annual TEPR conference and exhibition, Texas USA, 2003..
Tidd, J., Bessant, J., and Pavitt, K. “Managing Innovation: integrating technological, market and organizational change 2nd ed.”, West Sussex, John Wiley & Sons Ltd. 2001
Trevor Rohm, B.W. and Jr Tapie Rohm C.E. “Evolving medical informatics: from diagnosis to prognosis”, International Journal of Electronic Healthcare (1:1), 2004, pp.103-111.
Walters, D. and Jones, P. “Value and value chains in healthcare”, The TQM Magazine (13:5), 2001, pp.319-333.
Wen, J. and Tan, J. “The evolving face of telemedicine & e-health: opening doors and closing gaps in e-health services opportunities & challenges”, Proceedings of the 36th Hawaii International Conference on System Sciences, Hawaii, USA, January 6-9, 2003.
Wu, J.H. and Hsia, T.L. “An analysis of E-commerce innovation and the impact: A hypercube model”, Electronic Commerce Research and Applications (3:4), 2004, pp.389-404.